Certain phages in the gut are linked with increases in performance on some cognitive tests!
Microbe of the episode:
Streptomyces bikiniensis
News Item
Jesse's takeaways
Our gut microbiota includes a large number of viruses, mostly bacteriophages. These fall into two groups, the lytic kind that infects and reproduces itself immediately in a host, and the lysogenic kind that can integrate its genome into the host bacterial genome and remain dormant for long periods.
In this study, a higher proportion of lysogenic phages was correlated with increased performance on cognitive tests in multiple species. In humans, men showed a small increase in some tests and women in others. In mice and fruit flies, transplant or ingestion of phages was linked to increased memory performance.
In this study, a higher proportion of lysogenic phages was correlated with increased performance on cognitive tests in multiple species. In humans, men showed a small increase in some tests and women in others. In mice and fruit flies, transplant or ingestion of phages was linked to increased memory performance.
Journal Paper
Mayneris-Perxachs J, Castells-Nobau A, Arnoriaga-Rodr铆guez M, Garre-Olmo J, Puig J, Ramos R, Mart铆nez-Hern谩ndez F, Burokas A, Coll C, Moreno-Navarrete JM, Zapata-Tona C, Pedraza S, P茅rez-Brocal V, Rami贸-Torrent脿 L, Ricart W, Moya A, Mart铆nez-Garc铆a M, Maldonado R, Fern谩ndez-Real J-M. 2022. . Cell Host Microbe 30:340-356.e8.
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